BEST INDUSTRY PRACTICES TO ENSURE A SMOOTH SHUTDOWN AND A RAPID STARTUP

Once a cleanroom is built, the hvac system is operating and all equipment is installed, a meticulous initial clean is required prior to validation and use.

THIS IMPORTANT EVENT IS PERFORMED RAPIDLY, UNDER CLOSE CONTROL AND WITHIN THE CGMPS

 Phase One: Pre-Shutdown Activities (Planning and Scheduling)

Phase Two: Declassification and Handover

Phase Three: Day-To-Day Management and Handover

Phase Four: Reclassification and Handover

Phase Five: Post-Shutdown Activities and Completion of the Shutdown Report